For example, the percentage of CD4+/CD8+ T cells and the percentage of CD4 + CD45RA + T cells were increased, the percentage of CD8 + T cells and CD4 + CD45RO + T cells were significantly decreased, and the number of CD19 + B cells was reduced after IVIG treatment in GBS patients (27). This evidence concerns the gene CD8A and Guillain-Barre syndrome.