SLCO1A2 and Alzheimer disease: In this study, we aimed to examine the changes of Aβ1-42uptake in HEK293T, OATP1A2-HEK293T transgenic cells, and human astrocytes, to confirm, at the cellular level, whether OATP1A2 is involved in transporting Aβ1-42, as well as the expression of OATP1A2 and its transport of Aβ1-42 in neuronal cells that are closely related to AD.