A meta-analysis published in 2014 found that CRP had a sensitivity of 64%, specificity of 82%, and a positive likelihood ratio of 3.34 for detecting infected necrosis, whereas PCT had a sensitivity of 85%, specificity of 78%, and a positive likelihood ratio of 4.54.273 Procalcitonin was identified as the best test for predicting infected necrosis, with a higher positive likelihood ratio in patients with necrotizing pancreatitis compared to all patients with pancreatitis (9.3 vs. 4.5).273 However, it is important to keep in mind that PCT is a non-specific marker for infectious complications. This evidence concerns the gene CRP and pancreatitis.