CXCL8 and infection: Infection with BRSV leads to an increase in several cytokines and chemokines in circulation, including IL-6, TNF-α, IL-18, chemokine-x-c motif ligand (CXCL8), CCL2, CCL3, and CCL5, mediating the subsequent influx of leukocytes, predominantly neutrophils [159,160].