GPT and Acute hepatitis: An alternative approach to diagnosing incident HCV infection is to consider at least two of the following criteria: (a) the presence of symptoms and signs compatible with acute viral hepatitis, including jaundice; (b) an elevated alanine aminotransferase (ALT) level greater than five times the upper limit of normal; (c) the presence of risk factors or a history of exposure to HCV; (d) the absence of other known causes of acute hepatitis, including hepatitis A virus, hepatitis B virus, hepatitis D virus in chronic hepatitis B infection, and autoimmune hepatitis.