In our study, IFN was inhibited in CD4+, CD8+, and CD56+ lymphocytes in the presence of oncoproteins E6 and E7, and low amounts of IFN were found in the supernatants of lung cancer cells transfected with HPV oncogenes and co-cultured with lymphocytes and monocytes. The gene discussed is NCAM1; the disease is lung carcinoma.