The HLA-C, HLA-DQA1, and HLA-DRB1 alleles associated with the risk of HIV infection were C*07:01 (p = 0.0101, OR = 10.222), DQA1*03:02 (p = 0.0051, OR = 5.297), and DRB1*09:01 (p = 0.0119, OR = 4.788), respectively; the HLA-DQB1*03:419 (p = 0.0412, OR = 0.3273) allele can be considered a protective factor in this sample (Table 3). This evidence concerns the gene HLA-DQA1 and HIV infectious disease.