PIK3C2A and Thrombocytopenia: Regarding biochemistry alterations, the most frequently observed deviations were high levels of ferritin and C-reactive protein (CRP) (99%), urea (95%), lactate dehydrogenase (LDH) (77%), D-dimer (68%), gamma-glutamyl transferase (GGT) (57%), and aspartate transaminase (AST) (47%), it being also frequent to find high levels of alanine transaminase (ALT) (34%), hypoalbuminemia (28%), creatinine phosphokinase (CPK) (25%), neutrophilia (18%), thrombocytopenia, and high prothrombin time (17%).