Death, ICU admission, and the need for ventilation were found to be affected by the role of several risk factors (advanced age; diagnosis of obesity, cancer, diabetes and neuromuscular disorders; presence of abdominal pain and cough; low blood levels of oxygen saturation, platelets and albumin; and elevated blood levels of CPK, GGT, LDH, neutrophils, and elevated prothrombin time), as well as protective factors (diagnosis of hypertension and the presence of cough, sore throat, and vomiting). The gene discussed is F2; the disease is obesity due to melanocortin 4 receptor deficiency.