These results suggest that women infected with COVID-19 had comparable perinatal outcomes to those not infected during pregnancy; however, individual ACE2 genetic characteristics have a significant effect on pregnancy outcomes, as the recessive mutations of rs2158082 and rs4830974 were found to be associated with an increased risk of low birthweight and preterm birth, whereas the dominant mutation of rs2285666 (CT + TT) was associated with decreased odds of low birthweight. The gene discussed is ACE2; the disease is COVID-19.