IL18 and hypertensive disorder: Metabolic risk factors include abnormal blood lipid levels (total cholesterol, triglycerides, high-density lipoprotein, low-density lipoprotein), homocysteine, troponin T, inflammatory markers (C-reactive protein, IL-1, IL-6, IL-18, TNF-α, vascular and cellular adhesion molecules), and high blood pressure (BP), among others, as well as the presence of other conditions such as being overweight, obesity, diabetes, and hypertension [4].