The small number of CRC patients in the study sample was related to the low statistical power of the survival analysis and makes it impossible to perform, for example, multifactorial survival analysis (e.g., Cox’s proportional hazard regression model), which would help to identify factors influencing, in addition to preoperative serum NPY concentration, the deterioration of a patient’s nutritional status and risk, as well as a patient’s survival. The gene discussed is NPY; the disease is colorectal carcinoma.