The sensitivity of the model with CST1 (0.9032) is significantly higher than that of the model without CST1 (0.7097), and the specificity of the model with CST1 (0.8286) is higher than that of the model without CST1 (0.6571), indicating that the model with CST1 is better at correctly identifying AD patients and healthy controls. The gene discussed is CST1; the disease is Alzheimer disease.