More recently, a study demonstrated that the N6-methyladenosine (m6A) modification of hnRNPA2B1 in MM cells altered the associated miRNA processing thus leading to a high level of miR-92a-2-5p and miR-373-3p in their secreted exosomes, which enhanced osteoclastogenesis and suppressed osteoblastogenesis through blocking IRF8 or RUNX2 after being transferred into recipient monocytes or MSCs [33]. This evidence concerns the gene RUNX2 and Miyoshi myopathy.