Furthermore, they established MM cell exosomes presented with membrane-bound Hsp70 by the transfection of pcDNAHSP70 and found that it increased the expression of molecules such as lab, co-stimulatory molecules (CD40 and CD80), and inflammatory cytokines (IL-1β, TNF-α, Interferon-γ, and IL-12) [132]. Here, TNF is linked to Miyoshi myopathy.