They found that MICA*008 (MICA allelic variant) could be exposed on the surface of MICA*008 transfected MM cell-derived exosomes and MVs, which was able to augment the tumoricidal function of NK cells for a short time, but their prolonged stimulation downregulated NKG2D to inhibit NK cell function [49]. Here, KLRK1 is linked to Miyoshi myopathy.