Their data demonstrated that in vitro Olodateral blocked transforming growth factor (TGF)-β-induced myofibroblast differentiation and the fibroblast growth factor (FGF)- and platelet-derived growth factor (PDGF)-induced migration and proliferation of cells in both HLFs and IPF-LFs. This evidence concerns the gene TGFB1 and idiopathic pulmonary fibrosis.