NRP1 and cancer: These studies highlight the potential of dual-targeting tracers, such as 18F-AlF-NOTA-RGD-ATWLPPR and 68Ga-DOTA-RGD-ATWLPPR, in enhancing the precision of cancer imaging and therapy by effectively targeting both integrin αvβ3 and NRP-1, offering new avenues for advancing cancer diagnosis and treatment.