INS and Insulin resistance: At week 8, fasting blood glucose, area under the curve of oral glucose tolerance test (AUC of OGTT), serum insulin and homeostatic model assessment for insulin resistance (HOMA-IR) of the HCHF-induced rats (MS, MS+DeGT and MS+RGT) showed no significant difference compared to the C group or baseline (p > 0.05) (Figure 5a–d).