SRD5A2, SRD5A1, HSD17B1, AKR1C1, HSD17B2, AKR1C3, AKR1C2, CYP3A4, and CYP19A1 were significantly enriched in steroid hormone biosynthesis, and CCND1, ERBB2, MAPK1, AKT1, BRAF, PIK3R1, EGFR, and MAPK3 were found to enhance the endometrial cancer pathway (Figure 6B). Here, PIK3R1 is linked to endometrial cancer.