SRD5A2, SRD5A1, HSD17B1, AKR1C1, HSD17B2, AKR1C3, AKR1C2, CYP3A4, and CYP19A1 were significantly enriched in steroid hormone biosynthesis, and CCND1, ERBB2, MAPK1, AKT1, BRAF, PIK3R1, EGFR, and MAPK3 were found to enhance the endometrial cancer pathway (Figure 6B). The gene discussed is HSD17B1; the disease is endometrial cancer.