Less often, acromegaly may also be associated with the ectopic secretion of somatoliberin (GHRH, growth hormone-releasing hormone) or GH by NENs (NENs, neuroendocrine neoplasms), especially with the localisation of the primary tumour in the thymus, bronchi, or pancreas [5]. This evidence concerns the gene GH1 and neuroendocrine neoplasm.