Additionally, NPC1L1 expression increased in the high stage across ccRCC, cRCC, and chRCC, showing a trend toward higher expression, though none of the differences were statistically significant (ccRCC: p = 0.093, pRCC: p = 0.053, chRCC: p = 0.224) (Figure 3B–D). The gene discussed is NPC1L1; the disease is nonpapillary renal cell carcinoma.