For instance, tumor-suppressor miRNAs such as and miR-199b-3p [96], miR-129-3p [99], miR-490-3p [89], and miR-26a-5p [101] directly repress AURKA, whereas lncRNAs like MALAT1 [104] and TUG1 [120] indirectly upregulate AURKA by sponging and downregulating tumor-suppressor miRNAs. The gene discussed is TUG1; the disease is neoplasm.