The significantly elevated levels of TUG1 in adult AML patients (n = 186) positively correlated with poor prognosis and other characteristic features of the disease such as white blood cell count, monosomal karyotype, and FMS-like tyrosine kinase-3 internal tandem duplication (FLT3-ITD) mutation. This evidence concerns the gene TUG1 and acute myeloid leukemia.