The maternal HLA-DRB1*0301 (HLA-DR3) and HLA-DRB1*0401/040X (HLA-DR4), belonging to the major histocompatibility complex (MHC) class II reveals the critical role of autoimmunity in the pathogenesis of the PG due to their predominant correlation with the disease [1,29]. The gene discussed is HLA-DRB1; the disease is Autoimmunity.