Several antigens, such as Kiel 67 (Ki-67), pAkt, phosphorylated extracellular signal-regulated kinases (pErk), and phosphorylated signal transducer and activator of transcription 3 (pStat3), are involved in promoting cell proliferation and survival, with high expression commonly observed in aggressive cancers [14,15,16]. The gene discussed is STAT3; the disease is cancer.