In-hospital death rates were higher for people with peptic ulcer disease; confusion; shortness of breath; nausea or vomiting; muscle pain; headaches; shock; respiratory failure; mental changes; tachypnea (RR ≥ 22); a qSOFA score of 2 or more; higher BUN/CRP and lower albumin on the first day of hospitalization; higher PMN/ANC/BUN/potassium/CRP/total bilirubin and lower albumin after 7 days; a shorter ampicillin use duration; a longer treatment delay for ampicillin therapy; and combined E. coli bacteremia. The gene discussed is CRP; the disease is peptic ulcer disease.