NCAM1 and irritable bowel syndrome: However, a genome-wide association study identified six genetic susceptibility loci for IBS—NCAM1 (neural cell adhesion molecule 1), CADM2 (cell adhesion molecule 2, PHF2/FAM120A (PHD finger protein 2/family with sequence similarity 120 member A), DOCK9 (dedicator of cytokinesis 9), CKAP2/TPTE2P3 (cytoskeleton-associated protein 2/transmembrane protein with EGF-like and two follistatin-like domains 2 pseudogene 3), and BAG6 (BCL2-associated athanogene 6)—four of which are also associated with mood and anxiety disorders [35].