Another group [52] showed that severe asthma was neither TH1 or TH2, but severe asthma was characterized by elevations in BAL CXCL1 (growth-related oncogene, GRO), RANTES (regulated on activation, normal T cell-expressed and -secreted, CCL5), IL-12, interferon (IFN)-γ and IL-10. The gene discussed is CCL5; the disease is asthma.