The novel adiponectin–resistin (AR) index integrates the inflammatory and insulin-sensitizing properties of adiponectin and resistin, providing a holistic marker of inflammation and insulin resistance due to the importance of the aforementioned dual perspective in conditions like T2DM and MetS appreciating a positive correlation of AR index with the risk of developing T2DM and MetS [10]. This evidence concerns the gene ADIPOQ and Insulin resistance.