Lin et al. studied the effect of EPP on glucose metabolism in diabetic rats and found that EPP could improve glucose metabolism; the mechanism may be related to the antioxidant activity of EPP and its ability to regulate the mRNA levels of InsR, GCK, APN, and GLUT-4 genes in liver and adipose tissue, indicating the potential ability of EPP in the treatment of diabetes [79]. This evidence concerns the gene INSR and diabetes mellitus.