Nonetheless, in epithelial ovarian cancer, the developmental regulator NKX2-8 is able to transcriptionally inhibit CPT2 by recruiting the transcriptional repressor complex Sin3A/HDAC1/SAP18, and the combination of pegfilgrastim and platinum drugs enhances therapeutic effects in epithelial ovarian cancer [11]. The gene discussed is HDAC1; the disease is ovarian carcinoma.