In contrast, in colorectal cancer, a regulatory network formed by SGMS1-AS1 and microRNA-106a-5p exists upstream of CPT2, leading to a decrease in CPT2 expression and enhancement of glucose uptake and lactic acid production, resulting in an immunosuppressive tumor microenvironment that promotes the development of colorectal cancer [128]. Here, SGMS1 is linked to colorectal cancer.