Moreover, in CLL (chronic lymphocytic leukemia), perhexiline was found to selectively kill CLL cells expressing high levels of CPT1 and CPT2, with little effect on other cells, and a CLL transgenic mouse model further demonstrated in vivo that perhexiline injections significantly prolonged the survival of the animals [10]. The gene discussed is CPT1A; the disease is B-cell chronic lymphocytic leukemia.