BCHE and lymphopenia: Univariate analyses of factors associated with unfavorable outcome at 30 days revealed a significant association for age (for 5 y increase, OR: 1.5, CI: 1.11–2.02, p = 0.008), SAPS II score (for 1 point increase, OR: 1.05, CI: 1.01–1.1, p = 0.042), SOFA score (for 1 point increase, OR: 1.37, CI: 1.06–1.76, p = 0.017), lymphocytopenia (present or absent, OR: 32.5, CI: 3.45–306.4, p = 0.002), viral reactivation (OR: 9.75, CI: 1.72–55.4, p = 0.01), and cholinesterase drop up to <1600 U/L (OR: 39.7, CI: 5.8–271.6, p < 0.001; Table 2).