Additionally, LD was observed for loci rs2303426 and rs10179950 in MSH2 in both CRC (r2 = 0.7143, D’ = 0.8571; p < 0.0001) and reference (r2 = 0.8674, D’ = 0.9442; p < 0.0001) groups, and also for loci rs2286681 and rs62456178 in PMS2 in patients (r2 = 0.7027, D’ = 0.9323; p < 0.0001) and reference subjects (r2 = 0.6295, D’ = 0.9313; p < 0.0001). This evidence concerns the gene PMS2 and colorectal carcinoma.