The latest study found that ALG10B encoding α-1, 2-glucose-transferase B (ALG10B) protein is a new LQTS susceptibility gene, and the p.G6S mutant of ALG10B down-regulates ALG10B, resulting in human ether-a-go-go-related gene (HERG) transport defects and prolonged action potential duration [21]. The gene discussed is ALG10B; the disease is familial long QT syndrome.