TANGO2 and syndromic intellectual disability: Transport and Golgi organization 2 homolog (TANGO2) encodes a protein involved in the redistribution of the Golgi membrane to the endoplasmic reticulum, and its biallelic cutoff mutation causes defective mitochondrial fatty acid oxidation, leading to recurrent metabolic myogenic brain crisis/rhabdomyolysis/arrhythmia/intellectual disability syndrome [156].