SNRPN and obesity due to melanocortin 4 receptor deficiency: Other rare PWS cases presenting the PWS symptoms of overeating and obesity have emerged and have been described with small, atypical deletions overlapping PWS-IC or a partial deletion of SNURF-SNRPN, or even a microdeletion of 78 kb that includes SNURF-SNRPN exons 2 and 3 [11,12,13].