In vivo reestablishment of catalase expression, a H2O2 scavenger, via microinjection of an adenovirus carrying the catalase gene sequence into the ICG, decreased H2O2 levels, and improved CVP neuronal excitability, indicating that ROS is a driver of CVP neuronal dysfunction and ventricular arrhythmias in T2DM rats [73]. This evidence concerns the gene CAT and Ventricular arrhythmia.