Fused in sarcoma (FUS, also known as translocated in liposarcoma [TLS]), along with Ewing’s sarcoma (EWS) and TATA-binding-protein–associated factor 15 (TAF15), is a member of the highly conserved FET family of RNA-binding proteins that regulate mRNA metabolism and may be involved in DNA repair and participate in the organization of biomolecular condensates in vivo [1,2,3]. This evidence concerns the gene FUS and Tumor Lysis Syndrome.