In addition, an 8-week RE regimen accelerated GLUT4 translocation, protein kinase B (Akt) and protein kinase C (PKC) phosphorylation, and elevation of muscular DHT (5α-dihydrotestosterone) levels, improving fasting blood glucose and insulin sensitivity in T2DM rats [5,6]. Here, AKT1 is linked to type 2 diabetes mellitus.