VEGFC and open-angle glaucoma: Histological analysis reveals that VEGF-C is up-regulated in tissues involved in glaucoma pathogenesis, such as the trabecular meshwork, Schlemm’s canal, and aqueous humor collecting ducts, in a patient with POAG who underwent trabeculectomy, and also in a patient with neovascular glaucoma (NVG) secondary to proliferative diabetic retinopathy [45].