Not limited to ALS and FTLD, TDP-43 pathology has also been discovered in Tau- and Aβ-related diseases, such as AD [173,185,200,285,286,287,288,289], corticobasal degeneration (CBD) [191,192,193,194,290,291], progressive supranuclear palsy (PSP) [190,191,292] and argyrophilic grain disease (AGD) [195,196]. This evidence concerns the gene MAPT and Alzheimer disease.