In the case of WD, most of the serum copper is present in the form unbound to Cp—this is the so-called “free copper” (non-ceruloplasmin-bound copper: NCC) bound to albumin, alpha-macroglobulin, small peptides, and amino acids, which can accumulate in various tissues (including the brain and neurons) leading to oxidative stress (redox cycling reactions) and indirectly affecting sensitive tissues (including neurons), which can cause neurological and psychological symptoms of WD [17]. Here, ALB is linked to Wilson disease.