MAPT and amyotrophic lateral sclerosis: Tau has also been shown to accumulate in various human gene mutations associated with tauopathy brains [195] such as frontotemporal dementia (FTD)-associated CHMP2B [196,197,198,199], UBQLN2 [200,201,202,203], VCP [204] and SQSTM1 [205,206,207,208], and Parkinson’s disease (PD)-associated LRRK2 [209,210] and Pick’s disease (PiD), PSP, CBD-associated MAPT haplotypes [211,212,213], and ALS-associated C9orf72 [214] and TDP-43 [215,216].