CTLA4 and cutaneous mastocytosis: The present study aimed to verify, for the first time, associations of CTLA-4 c.-1577G>A, c.-1478G>A, c.-1765C>T, and c.-1661A>G SNVs with the risk and clinicopathologic aspects of CM and prognosis of patients treated with surgery and conventional chemotherapy, as well as to conduct functional analyses for clarifying their biological consequences.