FKBP51 has been implicated in metabolic disorders through its modulation of the insulin receptor pathway [38,39] and its correlation with leptin signaling [40], as well as by interacting with peroxisome proliferator-activated receptor-γ (PPARγ) [4,41] and regulating the energy sensor AMPK [42]. Here, FKBP5 is linked to Other metabolic disease.