ENST00000311550 (GABRB3) emerged as the most significant predictor for AD diagnosis, and additional mRNAs—ENST00000278765 (GGTLC1), ENST00000331581 (CADM1), ENST00000372572 (FOXJ3), and ENST00000636358 (ACY1)—were critical predictors of AD diagnosis (Supplementary Figure S1). This evidence concerns the gene GABRB3 and Alzheimer disease.