Syndromic IRDs are further subclassified according to the type of syndrome with Usher syndromes (USH1 [MIM: 276900], USH2 [MIM: 276901], USH3 [MIM: 276902]), which are characterized by sensorineuronal hearing loss and RP, followed by Bardet–Biedl (BBS [MIM: 209900]) and Alström syndromes (ALMS1 [MIM: 203800]), being the most prevailing subtypes [3]. The gene discussed is USH2A; the disease is Usher syndrome.