Moreover, studies observed an increase in blood lymphocyte counts, with notable elevations in specific T cytotoxic cell subsets (CCR4+CXCR3+ and CCR6+), as well as the presence of MHCII+ CD1d+ CD11b+ CD31+ monocytes in patients with Fabry disease [11,78,80,81]. Here, PECAM1 is linked to Fabry disease.