Recent reports have demonstrated that miR-138-5p exerts a repressive effect on the proliferation of endothelial progenitor cells by inhibiting hypoxia-inducible factor-1α (HIF-1α) and vascular endothelial growth factor A (VEGFA), both master regulators of angiogenesis and tumor vascular mimicry [97]. This evidence concerns the gene VEGFA and neoplasm.