In NPM1-mutated AML, Hox antisense intergenic RNA myeloid 1 (HOTAIRM1) was highly expressed and promoted leukemia cell autophagy by regulating early growth response 1 (EGR1) and unc-51-like autophagy activating kinase 3 (ULK3) [55]. Here, HOTAIRM1 is linked to acute myeloid leukemia.