Indeed, NFκB is recognized for the regulation of the transcriptional activity of over 400 genes, including those strongly related to inflammation (e.g., tumor necrosis factor alpha -TNFα, interleukin 1-IL-1, IL-6, and IL-8, or cyclooxygenase—COX2), for which elevated levels are a trailer of preeclampsia development [3]. The gene discussed is TNF; the disease is preeclampsia.