ZFP1 and infection: A recent study demonstrated that Avr-Pita targeted host mitochondria and directly interacted with a mitochondrial cytochrome c oxidase (COX) assemble protein (OsCOX11) of the mitochondrial electron transport chain to promote the COX activity in ROS metabolism, thereby inhibiting the ROS explosion and suppressing the congenital immunity in rice upon infection with M. oryzae [49].