CXCL8 and cancer: Among them were the pathways of the caspase cascade in apoptosis, TNF signaling, MAPK signaling, Ras signaling, ErbB signaling, Wnt signaling, TGF-beta, mTOR, chemotaxis driven by IL-8 and LTB4, cell adhesion regulated by cadherins, Notch signaling, STAT3, proteoglycans in cancer, development of immune synapse, HGF signaling, p38 signaling, and JNK signaling.