In addition to variations in the RyR2 gene, other, less common genetic modifications associated with CPVT have been identified, involving genes such as TRDN (603283), the calmodulin gene family CALM1 (114180), CALM2 (114182), and CALM3 (114183), ANK2 (106410), and TECRL (617242) [69]. This evidence concerns the gene RYR2 and catecholaminergic polymorphic ventricular tachycardia.